Dr. Andrea Gore, a professor of pharmacology and toxicology in the College of Pharmacy, specializes in reproductive neuroendocrinology and the mechanisms by which the brain controls reproductive function. She received a $1.4 million grant from the National Institutes of Health to study how the brain may play a role in controlling the timing of menopause. Gore is one of several researchers who are realizing that a deeper understanding of the brain's role in reproductive failure is needed to help in the creation of new therapies. She also is studying how environmental endocrine-disrupting chemicals (EDCs) such as polychlorinated biphenyls (PCBs) alter reproductive neuroendocrine function. This study looks at the effects of fetal PCB exposure on reproductive development and physiology, mating behavior and transgenerational effects.